HDC GENE ONTOLOGY
ONTOLOGY
Ontology is the philosophical study of "being". It can be broken down into 3 different aspects:
1 BIOLOGICAL PROCESSES: the activities of the cell the gene product is involved in
2 CELLULAR COMPONENTS: cell parts the gene product is active in
3 MOLECULAR FUNCTIONS: what molecular component the gene product interacts with
1 BIOLOGICAL PROCESSES: the activities of the cell the gene product is involved in
2 CELLULAR COMPONENTS: cell parts the gene product is active in
3 MOLECULAR FUNCTIONS: what molecular component the gene product interacts with
Hdc ONTOLOGY [1]
BIOLOGICAL PROCESSESCatecholamine biosynthesis
chemical reactions and pathways resulting in the formation of a physiologically important biogenic amine, or neurotransmitter. Histamine biosynthetic process the formation of histamine. Histidine catabolic process the breakdown of histidine. |
CELLULAR COMPONENTSCytosol
a part of cytoplasm that does not contain organelles, but does contain protein complexes |
MOLECULAR FUNCTIONSHistidine decarboxylase activity
the process of converting histidine to histamine Lyase catalyzes the breaking of chemical bonds Pyridoxal phosphate binding the process of interacting selectively and non-covalently with the active form of vitamin B6 |
ANALYSIS
The processes and molecular functions were no surprise. Histidine carboxylase's main role is catalytic and enzymatic while helping transform histidine to histamine. Checking gene ontology is important because sometimes genes and proteins can have surprising roles within the body.
REFERENCES
1 "P19113 (DCHS_HUMAN)" UniProtKB/Swiss-Prot. Retrieved 20 Feb 2014 http://www.uniprot.org/uniprot/P19113#section_terms
1 "P19113 (DCHS_HUMAN)" UniProtKB/Swiss-Prot. Retrieved 20 Feb 2014 http://www.uniprot.org/uniprot/P19113#section_terms
University of Wisconsin – Madison
Spring 2014 Genetics 564 |
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